Pediatrics Compounding Maryland

HEALTHY KID, HAPPY FAMILY!

We work together with prescribers, children, and their families to customize medications and meet their specific needs.

Children pose many challenges when it comes to medication: they may resist having to take a medication, dislike the taste or texture, have difficulty swallowing solid dosage forms, and are fearful of injections.

The limited pediatric market for most drugs may be the leading reason for the lack of investment in drug development for this population by the pharmaceutical industry. Most medications are not labeled for pediatric populations, and when a medication is not approved for use in infants and children, it usually is not available in a suitable pediatric dosage form. Fortunately, our compounding pharmacy is able to help.

We can compound oral medications into pleasantly flavored suspensions, solutions, concentrates, freezer pops, “gummy bears” or lozenges, in colors that entice the child to take the medication. A palatable formulation is more likely to improve compliance and minimize spillage or waste during administration. Lollipops are an ideal alternative to “swish and swallow” medications that need to be retained in the mouth for a prolonged period of time. Most drugs can be compounded into transdermal gels that can easily be applied to an appropriate site, such as the child’s wrist, for absorption through the skin.

Professional compounding is not just diluting existing medications, or mixing powders with bases. We must consider physical and chemical properties of each active and inactive ingredient in order to prepare an effective and safe customized medication with the desired taste, color, fragrance, viscosity, uniformity, texture, and stability. The efficacy of any compounded medication is influenced by the technique and equipment used in preparing the formulation, the purity and quality of the ingredients, choice of vehicle (base), and proper use of additives such as penetration enhancers.

Attention Deficit Hyperactivity Disorder (ADHD)

The use of medications to treat ADHD has greatly increased, yet the dosage requirements for many children differ from strengths that are commercially available. This often necessitates a midday dose at school, which can be embarrassing to a child. Slow-release dosage forms can be compounded to contain the precise dose of medication needed.

Autism

Autism is a neurodevelopmental disorder. It is characterized by impairments in social relatedness and communication, repetitive behaviors, abnormal movements, and sensory dysfunction. A review of some of the current biomedical therapies-such as nutritional supplementation, chelation, and secretin suggests that these therapies may benefit autistic children.

The Autism Research Institute has asked parents to rate the effectiveness of numerous biomedical treatments. Over 23,000 parents have responded, and of 77 interventions, Mercury detoxification was rated helpful by 73% of parents, with the gluten/casein-free diet coming in second with 63%.

Transdermal Medications

We can compound medications in transdermal gels that can easily be applied to an appropriate site, such as child’s wrist or back, for absorption through the skin.

Flavoring

We can compound oral medications into pleasantly flavored suspensions, solutions, concentrates, lozenges. A palatable formulation is more likely to improve compliance and minimize waste.

Gluten-Free and Casein-Free Medications:

Children with Autism may benefit from gluten-free and casein-free diet.

Gluten is a mixture of wheat proteins, and proteins from other grains such as rye, oats and barley. many commonly used medications-antibiotics, decongestants, and pain relievers including acetaminophen and ibuprofen-may contain gluten. Even flavors can contain gluten.

Casein is a milk protein commonly found in dairy products. we can compound medications that are free of gluten, casein, lactose, sugar, dyes and alcohol to solve problems for sensitive individuals.

Diaper Rash

Customized formulations containing protectants, absorbents, and bile acid sequestrant can provide relief for baby’s irritated skin. We can also compound medications, such as cholestyramine ointment, to prevent site irritation in ostomy patients/ babies.

Some examples for the compounded combination for diaper rash or baby's irritated skin are:

  • Combination of Cholestyramine, Zinc oxide, and Nystatin ointment
  • Combination of Sucralfate, Zinc oxide, and Nystatin ointment

Nipple healing Ointment

Nipple soreness while breast feeding can be caused by different reasons:

There are some medications that are typically prescribed in different strengths for treatment:

  • Mupirocin: an antibiotic, used to treat infections caused by bacteria
  • Clotrimazole/Nystatin: antifungals, used to treat some types of fungal or yeast infections
  • Betamethasone: a corticosteroid used to treat irritation, swelling, redness, itching, and allergic reactions

Acne

Emergence of resistant pathogens emphasizes the need for alternatives to antimicrobial agents for acne therapy. We can compound cosmetically-appealing customized formulations which can contain numerous medications to provide a synergistic effect for treatment of resistant acne.

Travel medicine

We prepare following formulations for protection against malaria prophylaxis in small dosages that are not commercially available for kids:

  • Chloroquine Phosphate
  • Mefloquine Hydrochloride
  • Primaquine phosphate

Please note that no antimalarial drug is 100% protective and must be combined with the use of personal protective measures, (i.e., insect repellent, long sleeves, long pants, sleeping in a mosquito-free setting or using an insecticide-treated bednet).

Pediatrics: Examples of compounded medications

  • BLT gel or transdermal cream
  • Cholestyramine ointment
  • Clotrimazole in DMSO solution
  • Fluconazole/Ibuprofen topical
  • Ivermectin topical
  • KOH solution – 5% and 10%
  • Nicotinamide/Spironolactone topical
  • Promethazine transdermal gel

The above list is just a few of the preparations that we can compound for pediatric use. We work together with prescriber and patient to solve problems, and all formulations are customized per prescription to meet the unique needs of each child.

our compounding professionals can prepare

tailored medication for your condition

multiple medication in a single dose

various formulation for easy application

not commercially avaiable medication

CONTACT US FOR YOUR COMPOUNDING NEEDS!